Stomach pain or Paralysis In rare cases, semaglutide may cause gastroparesis, in which the stomach empties food more slowly than usual
Even at low doses, GLP-1 medications carry a risk of serious side effects, such as acute pancreatitis or gallbladder disorders
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For example, the SELECT trial clearly demonstrated that semaglutide significantly reduces the risk of major adverse cardiovascular events (MACE), leading to FDA approval for lowering the risk of cardiovascular death, myocardial infarction, or stroke in overweight or obese adults with established cardiovascular disease (Lincoff et al., 2023
Coordination between endocrinology, primary care, and cardiology teams can help ensure safe and effective integration
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