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It's the same active ingredient semaglutide, a GLP-1 receptor agonist that curbs appetite and slows gastric emptying

62 RGT075 RGT075 is a small oral GLP-1RA identified through Computer-Accelerated Rational Design (CARD) with potent G-protein-coupled cAMP signaling

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As a result, significant efforts are being made to develop long-acting GLP-1R agonists, through the substitution of a susceptible amino acid in GLP-1 into a mutant to confer resistance to DPP-IV degradation 12 and the significantly prolonging of GLP-1 half-life via the virtue of the neonatal Fc receptor (FcRn) recycling mechanism through binding to IgG-Fc 13 or human serum albumin (HSA) 14