Furthermore, in another meta-analysis [23], which excluded ELIXA [24] due to fact that lixisenatide is a short-acting GLP-1RA and all participants had acute coronary syndrome, GLP-1RAs were associated with significant reductions in MACE (HR 0.85, 95% CI 0.800.90), cardiovascular death (HR 0.85, 95% CI 0.780.93), stroke (HR 0.81, 95% CI 0.740.90), and myocardial infarction (HR 0.88, 95% CI 0.810.96) (Table 2)
If you are comparing GLP-1 categories, our compounded tirzepatide guide explains why approved, compounded, and investigational products should not be treated as the same category
Additional markers like FTO rs9939609 and MC4R rs17782313 assess genetic predisposition to obesity and appetite dysregulation
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