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Our earlier preview of the seven peptides under FDA review explains what each compound does and why it was nominated.

Testing must be performed by a mutually accepted, established specialist laboratory

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Data was acquired in positive mode using parallel reaction monitoring with an inclusion list of acylcarnitines of interest (see Supplementary Table S4)

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Thus, the data from this study support the notion that BH4 can improve oxidative damage and methylation abnormalities in children with ASD with a large effect size, with the caveat that this effect may be more pronounced in those with the more severe abnormalities at baseline