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When fat enters the duodenum (the first part of the small intestine), it triggers the release of cholecystokinin (CCK) and other hormones that signal the stomach to slow its emptying rate

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Importantly, the increased IDO activity is a crucial mechanism related to the inflammation-induced depressive-like behavior by endotoxemia [233], thus showing the relevance that gut dysbiosis and bacterial translocation may have on BD patients

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