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PMID: 29155147

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However, there are considerations for dose adjustment based on individual tolerance

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So the goal is to get people to take as much of the drug as they can stand (preferably the highest allowable dose) in order to MAXIMIZE the side effect of weight loss

Adults are typically composed of 60% water, two thirds inside cells and one third in the extracellular space, giving our skin turgor and allowing nutrients to flow from our blood vessels into cells