4 For example, ADA and KDIGO joint group has recommended that for patients with T2DM and CKD who do not achieve their glycemic target with metformin and/or an SGLT2i or cannot use them, a GLP-1RAs with proven cardiovascular benefit is recommended
M., Brennan, A
Patients in the phase 3b clinical trial maintained about 75-80% of their weight loss and health benefits, such as reduced waist circumference and improvements in blood pressure, blood sugar, triglycerides and cholesterol levels
with a clinician, he says
Measure hematologic parameters on an annual basis and vitamin B12 at 2- to 3-year intervals in patients on XIGDUO XR and manage any abnormalities [see Adverse Reactions (6.1)]
By simultaneously aiming at GLP-1, GIP, and glucagon receptors, these drugs, such as retatrutide, deliver significantly greater efficacy than current therapies, expanding the addressable patient base