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[11] Adverse effects reported in the Walker 1990 trial and subsequent case series include injection site redness (approximately 17% of subjects), transient facial flushing (8%), and headache (6%)

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10.65 years (M)), but this was also without statistical significance

It has been revealed that prolonged exposure to stress triggers biological mechanisms, in particular those related to the regulation of the inflammatory cascade, which plays a key role in the pathogenesis of many diseases