Lu P, Takai K, Weaver VM, Werb Z
Structural studies have revealed that this strong preference is due to geometrical and conformational constraints that occur between a cofactor and a cofactor binding site on the LBD (PDB: 1T7R) 82,84
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More researches are still required to answer the temporal modulation, mechanisms of molecular and signaling pathways, and consequences of the BBB leakage in diabetes
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