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1,4 About POMC, PCSK1, and LEPR deficiencies Rare autosomal recessive disorders 2 Lead to hyperphagia and early-onset, severe obesity, mainly due to genetic variants in the MCR4 pathway 2 Can be difficult to diagnose based solely on clinical manifestations, so genetic testing is required to confirm a diagnosis 1,5 Learn if IMCIVREE may be appropriate for your patients with POMC, PCSK1, or LEPR deficiency

These side effects are normal and typically resolve on their own within a day or two of treatment

BAFF signaling in B cell metabolism

Unlike your stomach, for example, which shouts loudly if theres an issue, your liver and its functional partner the gallbladder are a quieter pair

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