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Alterations in the MET kinase domain trigger its phosphorylation, initiating a cancer-causing signaling cascade that leads to the continuous activation of the MET receptor [23, 25, 26]

But TB-500 as sold in grey markets is not the same thing as a well-characterized pharmaceutical product, and the FDAs Category 2 listing includes Thymosin Beta-4, Fragment (LKKTETQ) as a substance raising significant safety risks in compounding contexts

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