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Each compound targets distinct neurobiological pathwaysneurotrophism (BDNF), GABAergic modulation, neurotransmitter regulation, or sleep architecture

[DOI] [PubMed] [Google Scholar] 14.Abati S., Sandri G.F., Finotello L., Polizzi E

Advanced dosing considerations Beyond the standard titration, several dosing strategies merit discussion for patients and prescribers looking to optimize outcomes

conducted a parallel 12-week study

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On 5-on/2-off it is 10 doses = 1,000 mcg (1.0 mg)