Davidson, S
They may ameliorate OS by controlling the production of ROS, improving mitochondrial dysfunction of cells, scavenge free radicals, or enhance antioxidant defense enzymes and their related pathways, such as Nrf2 pathway, oxygenase-1 (HO-1) pathway, Kelch-like ECH-associated protein 1 (Keap1) pathway, and antioxidant response elements (ARE) pathway to improve OS-induced insulin resistance (Nishikawa et al., 2000
We faced a diabesity epidemic where the available tools were blunt instruments at best
Diabetes 45:10241029 Heitzer T, Finckh B, Albers S, Krohn K, Kohlschutter A, Meinertz T (2001) Beneficial effects of alpha-lipoic acid and ascorbic acid on endothelium-dependent, nitric oxide-mediated vasodilation in diabetic patients: relation to parameters of oxidative stress
These drugs help people lose a significant amount of weight, but muscle retention during weight loss is a critical concern that often gets overlooked
In late-onset keratosis pilaris occurring in adulthood, one needs to consider a drug as a possible cause
