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Finally, patients should understand that if urgent or emergent colonoscopy is required, the procedure may need to proceed regardless of medication status, with the anesthesia team taking appropriate precautions based on individual risk assessment

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Changes in skin sensation: Around 7% of participants reported changes in skin sensation, such as tingling or hypersensitivity

But because the receptors have already partially adapted, the effects are milder than they would have been if you had started at the higher dose from the beginning

[DOI] [PubMed] [Google Scholar] 10.Castillo C, Bogardus C, Bergman R, Thuillez P, Lillioja S