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Animal studies have demonstrated increased expression of tumor necrosis factor (TNF-) and microglial activation in the auditory cortex following noise-induced hearing loss, high-lighting a strong connection between neuroinflammation and tinnitus 9

KoganIRamjeesinghMLiCKiddJFWangYLeslieEMet alCFTR directly mediates nucleotide-regulated glutathione flux

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