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What the retatrutide trials measured Retatrutide (LY3437943) is a synthetic 39-amino-acid peptide engineered to act simultaneously at three class-B G-protein-coupled receptors: the GLP-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIPR), and the glucagon receptor (GCGR)

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And brand-name GLP-1s sit at a price point that may be out of reach for most consumers

doi: 10.1111/dom.12786 25 MosenzonOWeiCDavidsonJSciricaBMYanuvIRozenbergAet al