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Research Overview Nicotinamide N-methyltransferase (NNMT) catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide, producing 1-methylnicotinamide and S-adenosyl-L-homocysteine [1]

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10.1093/ajcn/nqaa221 18 DoetsE

Using a smaller syringe means you physically cannot draw 60 units, and attempting to force more liquid than the syringe can hold creates a mess and a wasted dose