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OSF patients typically exhibit reduced levels of collagen-degrading enzymes, such as matrix metalloproteinases (MMPs), as well as elevated levels of tissue inhibitors of metalloproteinases (TIMPs), thereby leading to an accumulation of fibrous tissue in the oral submucosa

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It is characterised by silver-white scales, inflammatory cells in the epidermis, keratinocyte hyperproliferation, and lesions [328]

Ning P, Liu C, Kang J, LvJ

The combination might successfully minimize renal damage of A on C patients, enhance restoration of kidney functionality, and relieve clinical symptoms in these individuals

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