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Activation of this receptor: Triggers the release of growth hormone-releasing hormone (GHRH) Directly stimulates growth hormone (GH) secretion from the pituitary gland Increases pulse amplitude of GH release, promoting more youthful and physiological GH patterns GHRP-2 increases pulsatile growth hormone release through binding to specific GHS-R receptors, resulting in enhanced GH secretion and IGF-1 production. Cordido et al., Journal of Clinical Endocrinology & Metabolism Synergistic with GHRH (CJC-1295) One of the most powerful aspects of GHRP-2 is that it works synergistically with GHRH analogs such as CJC-1295 (CJC-1295)

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