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These pathogenic bacteria can colonize the gut by exploiting epithelial damage and activate TH1/TH17 immune responses through virulence factors, such as the type III secretion system ( The data mentioned above indicate that the pathogenic potential of specific microorganisms in IBD is subject to multifactorial regulation, encompassing genetic background, environmental factors, and the composition of the gut microbiota

VIP for food allergies A study published in Immunopharmacology and Immunotoxicology found that VIP administration inhibited food allergy responses through restoration of immune suppressive functions in B regulatory cells

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Zhou Y et al (2018) Autocrine Mfge8 signaling prevents developmental exhaustion of the adult neural stem cell pool