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There is evidence that controlling acidosis reduces mitochondrial dysfunction in shock
However, the viral infections also are related with diseases in the CNS characterized by the presence of leukocyte infiltration and inflammation, inducing a progressive damage [1], such as the progressive multifocal leukoencephalopathy with the John Cunningham virus (JC), AIDS-related dementia complex observed in HIV-1-infected patients, neurodevelopmental sequelae (mental retardation, cerebral palsy, and sensorineural hearing loss) caused by congenital cytomegalovirus (CMV) infection or cerebral mass lesions in immunocompromised adults CMV-infected, and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) that affects the human T-cell lymphotropic virus type 1 (HTLV-1)-infected individuals
Funding This work was supported by the National Natural Science Foundation of China (NSFC) (82574019), the Science Technology Project of Jiaxing-Key Research Project (2024BZ20004), the National Health Commission Research Foundation (WKJ-ZJ-2305), the National Natural Science Foundation of China (No.82404522), and the Zhejiang Provincial Natural Science Foundation of China (No
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Emphasis is placed on the mechanisms by which probiotics inhibit H
