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This is supported by Wang et al.s work demonstrating that MMP-9 inhibitory activity of GEN and its inhibition of multiple signal transduction pathways such as MAPK, inhibitor of NF-B (IB), and phosphoinositide 3-kinase (PI3K)/Akt could control the invasiveness and metastatic potential of HCC (Wang et al., 2014)

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Cell Death Dis 13(6):530 Dang R et al (2022) Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway

Procedia Technol 10:381391 Singh SR, Sharma S (2017) A production reliable model for deteriorating products with random demand and inflation