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Creates more continuous release pattern

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2016 Jun 1;21(7):1314-29

BaiRChangYSaleemAWuFTianLZhangSet alAscorbic acid can promote the generation and expansion of neuroepithelial-like stem cells derived from hiPS/ES cells under chemically defined conditions through promoting collagen synthesis

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Key signaling pathways underlying CSC maintenance and therapy resistance The functional identity of CSCsmarked by their self-renewal and differentiation potentialrelies heavily on the activation of key signaling pathways that orchestrate tumor initiation, progression, and treatment resistance