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doi: 10.1089/bari.2015.0023 31

When the gauge reads low, AMPK triggers a coordinated set of responses designed to restore balance: increasing glucose uptake, burning stored fat for fuel, stimulating the production of new mitochondria, and temporarily suspending energy-consuming processes that are not immediately essential

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Also, both studies had timelines that averaged less than three years, which is a relatively short period for the onset of dementia

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