Im not sure there is any valid reason to use this product
The widely repeated claim that Dihexa is "seven orders of magnitude more potent than BDNF" originates from that flagged McCoy paper and reflects an assay-specific in-vitro spine-density measurement picomolar Dihexa versus nanomolar BDNF in one assay not a millions-fold advantage in a living brain
In contrast, PG-102 achieved a ~450 mg/dL glucose reduction and ~5% HbA1c decrease by 2-months, restoring normoglycemia and maintaining efficacy throughout the 3-month study (Fig
Abdelmalek MF, Suzuki A, Sanchez W, et al
The incidence of these reactions doesnt appear very different between retatrutide and tirzepatide
CYP2R1 expression was not seen in FL83B mouse hepatocytes) and 1--hydroxylase (CYP27B1), along with the increased expression of 24-hydroxylase (CYP24A1), was observed in GSH-deficient hepatocytes