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[2] Additionally, GLP-1 agonists have been shown to reduce markers of systemic inflammation, including C-reactive protein (CRP), in patients with type 2 diabetes and cardiovascular disease, though these reductions are often modest

In contrast, the minimally additive effect of exogenous GHRH with endogenous GHRH in the adult subjects reflects an age-related decline in the latter neuropeptide and of increased somatostatin tone with advancing age 17

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A standard increase may be excessive, while a lower dose may be ineffective

A novel neurotrophic property of glucagon-like peptide 1: A promoter of nerve growth factor-mediated differentiation in PC12 cells