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5, (6)carboxyfluorescein Diacetate (CFDA

Contraindications exist for patients with seizure disorders, uncontrolled blood pressure, or opioid dependence

By week 88, the placebo group had regained roughly half of what they originally lost

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The flexible dose-adjustment approach allowing patients to escalate or de-escalate doses of the drug on the basis of their HbA1c and gastrointestinal tolerability (PIONEER-7) aimed to individually optimize efficacy and safety of once-daily oral semaglutide in T2D adults uncontrolled with one or two oral glucose-lowering drugs, compared to 100 mg/day of sitagliptin