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Although some GLP-1RAs do not seem to naturally cross the bloodbrain barrier, they may still reach relevant brain areas via circumventricular sites and, possibly, via active transporters 4,5

You may experience some GI upset or other side effects

Communicate your current medication, dosage, and treatment history clearly during the intake process so your MEDVi provider can create an appropriate continuation plan

Survodutide developed through Boehringer Ingelheims research program focused on glucagon and GLP-1 receptor dual agonism

The molecular weight barrier and oral bioavailability limitation apply regardless of dose

Calcium intake may be harder to maintain through food alone