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The binding of B12-IF complex to the cubam receptors triggers receptor intake where the whole B12-IF-cubam receptor complex is taken into the ileal cell

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A multicenter, randomized, double blind, placebo-controlled phase II study of PL 14736 enema in the treatment of mild-to-moderate ulcerative colitis

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J Clin Endocrinol Metab 85 : 15181524 Acerini CL et al