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Why it matters: Approval status affects what can be prescribed, dispensed, labeled, and monitored in routine care

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The treatment of obesity and overweight is undergoing a transformation, and its increasingly clear that we need a broad range of medications and therapies to help people not only lose weight, but most importantly, maintain their ideal weight long-term

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Our previous research has shown that phosphoglycerate kinase (PGK1) induces glucose metabolic disorders in GCs, thereby exacerbating androgen-induced cytotoxicity 12