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Clinical trials published in the New England Journal of Medicine showed that people taking semaglutide lost significantly more weight than those taking a placebo

7 in a statement to Fortune

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Current data from ongoing trials indicate that appropriate candidates for retatrutide generally include: Adults aged 18 or older with a BMI of 30 kg/m or greater

But tirzepatide has already proven itself across multiple large-scale trials involving tens of thousands of participants, with established dosing protocols, known side effect patterns, and widespread clinical use