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Clinical studies demonstrate that GHK-Cu: Improves skin elasticity Reduces fine lines in some cosmetic studies Increases dermal thickness Enhances wound healing in limited models However: Most trials are small Many are cosmetic rather than mechanistic Long-term systemic data are limited Claims regarding hair regrowth and systemic anti aging effects exceed what controlled human trials demonstrate

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Schoenenberger, The influence of synthetic DSIP (delta-sleep-inducing-peptide) on disturbed human sleep, Springer Science and Business Media LLC, Sep

But according to a 2011 study , vitamin B12 overdose might paradoxically produce many of the same symptoms as deficiency

Long-term human safety and efficacy remain under investigation [4]