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Vial Duration At 1 mL weekly 10 weeks per vial At 1 mL twice weekly 5 weeks per vial At 0.5 mL weekly 20 weeks per vial Final Simplified Protocol Draw: 1 mL (100 units) = 1 mg B12 + Lipo-C blend Frequency: 12x per week Cycle: Ongoing for energy, fat metabolism, and wellness research Vial Supply: 520 weeks depending on frequency & dose

free-drug occupancy method (albumin Kd 1.86 uM, free fraction 0.29%): Willard JCI Insight 2020

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B-2 is needed for healthy digestive tract mucous membranes

Also, patients should be warned about the danger of taking folic acid in place of vitamin B 12, because the former may prevent anemia but allow progression of subacute combined degeneration