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Small bone injuries (less than 6 mm in diameter) often heal spontaneously in a favorable microenvironment, while larger bone defects typically require surgical intervention and bone substitutes (Koushik et al., 2023)

Due to the high reactivity of Sec residues and the accessible position of the C-terminal active site, TrxR has broad substrate specificity (29)

From a practical standpoint, the most defensible position remains planned exposure avoidance: explicit fertility planning, reliable contraception during treatment, label-informed discontinuation before conception attempts, immediate cessation once pregnancy is recognized, and active metabolic maintenance during the washout period to reduce rebound-related gestational risk (132137)

The peptide shares 94% structural homology with native human GLP-1, the hormone your body naturally produces to regulate blood sugar and appetite