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Detecting atrophic gastritis upon gastroscopy strongly supports the diagnosis, as does a positive finding of autoantibodies against intrinsic factor in a blood sample

It rests on NAD+ decline being an aging driver and on MOTS-c extending healthspan in mice [1][3]

Deficiencies can occur with medical conditions such as atrophic gastritis (which causes thinning of the stomach lining), pernicious anaemia, Crohns disease, celiac disease, lupus, or other immune system disorders and certain medications

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So, who is most at risk for developing this deficiency

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