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While human clinical data on GHK-Cu's cognitive effects is still sparse, the current evidence and the compound's known influence on gene expression networks involved in neuronal survival are noteworthy

Control groups received saline injections

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10.1186/s12943-020-01258-7 Summary Keywords ulcerative colitis, GHK-Cu, SIRT1/STAT3 pathway, co-culture system, network pharmacology, molecular docking Citation Mao S, Huang J, Li J, Sun F, Zhang Q, Cheng Q, Zeng W, Lei D, Wang S and Yao J (2025) Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms

Internal changes during this phase include upregulation of collagen genes, increased growth factor production, and early accumulation of new extracellular matrix components

Additional chaperones target copper to specific organelles