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Chemical Structure: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 (13 AAs) Alternative Names: Scenesse, Melanotan 1, Afamelanotide CAS Number: 75921-69-6 WHAT IS MT-1 The MT-1 peptide, officially known as Afamelanotide, is a synthetic analog of the naturally occurring alpha-melanocyte-stimulating hormone (alpha-MSH)

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In contrast, such a tolbutamide-sensitive increase in K + currents was not detected in Kcnj11 / cells when dialyzed with ATP-free medium, confirming the absence of functional K ATP channels (Figure 1A)

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doi: 10.1007/s12020-021-02730-0 Summary Keywords growth hormone, insulin-like growth factor, GLP-1RAs, SGLT-2is, diabetes Citation Cignarelli A, Genchi VA, Le Grazie G, Caruso I, Marrano N, Biondi G, DOria R, Sorice GP, Natalicchio A, Perrini S, Laviola L and Giorgino F (2022) Mini Review: Effect of GLP-1 Receptor Agonists and SGLT-2 Inhibitors on the Growth Hormone/IGF Axis