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The pain tends to lessen with gradually increased activity but worsens toward the end of the day with increased duration of weight-bearing activity

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Still, excessive intake above 400 mcg a day from food and supplement sources combined -- can be problematic because it can lead to selenium toxicity, which can cause hair loss, gastrointestinal upset, and other health issues

doi: 10.3390/jcm12010145

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Older patients may find that visiting their doctors for a monthly B12 shot is the easiest way to supplement their intake oral B12 replacement is largely ineffective in older patients, Dr