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When compounded professionally, it is well tolerated for daily topical use

Evidence suggests that the catalytic conversion of hypotaurine to taurine is the function of the enzyme encoded by the FMO1 (flavin containing dimethylaniline monoxygenase 1) gene

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Most available research and data come from rodent studies

Yang, C

Later studies, combining purified human proteins or human liver microsomes with specific inhibitors confirm the role of CYP2E1 in bioactivation of toxic levels of APAP, but also report involvement of CYP2A6 [31,32]