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W., Wilborn, C

Clin Endocrinol (Oxf) (2006) 64(4):36670

They are not strictly necessary for subcutaneous self-injection, but they reduce the chance of introducing bacteria during reconstitution

Zhang QY, et al

This is critical for maintaining receptor sensitivity and avoiding the tachyphylaxis often seen with other agents

Given the nonspecific and varied presentations, clinicians must maintain a high index of suspicion to avoid delays in diagnosis, which can significantly impact prognosis

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