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It is a tightly regulated reaction that depends on both the availability of the amino acids (cysteine, glycine, and glutamate) and the rate-limiting enzyme, glutamate-cysteine ligase ( GCL )

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Regarding hematological parameters and inflammatory mediators, mice from saline-CLP group showed a significant augment in the number of circulating total leukocytes (Figure 2C), monocytes (Figure 2D), neutrophils (Figure 2E), and platelets (Figure 2F)

Eur J Endocrinol 175:325333 Hoogenberg K, Sluiter WJ, Dullaart RP (1993) Effect of growth hormone and insulin-like growth factor I on urinary albumin excretion: studies in acromegaly and growth hormone deficiency

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