Setting Realistic Expectations for Non-Surgical Options Non-surgical treatments can improve skin quality and provide subtle tightening but cannot remove excess skin or achieve surgical-level results
The question isn't just "how much weight can we help patients lose?" but "how do we match the right therapy to the right patient at the right time?" The 28% weight loss is remarkable, but the higher discontinuation rates remind us that efficacy on paper doesn't always translate to real-world success
The Bottom Line Microdosing GLP-1 reflects a real patient concern: balancing effectiveness, tolerability, cost, and long-term planning
1 Nonmotor symptoms are a separate category of symptoms that patients with PD may experience that do not affect movement but are still negatively impactful
Three mechanisms working in concert, each amplifying the others
42,43 Of note, Abbass et al did not control for hemoglobin A1c, lipid levels, or history of cataract surgery, which could introduce bias
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