Therefore, enhancing bioavailability and stability will be key in the future, although breakthroughs in once-weekly oral GLP-1 drugs are still awaited
These drugs last longer than the natural version, which allows them to keep working throughout the day
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One paper suggested that GLP-1s may improve some gut health symptoms (such as abdominal pain) but worsen others (such as regularity and constipation)
Although GLP-1RAs are well established for treating obesity, type 2 diabetes, and for reducing cardiovascular risk, their potential role in inflammatory diseases such as RA has not been clearly defined