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Second, we excluded patients who had any TZD records during follow-up from the cohort entry date (i.e., GLA initiation) to the index date (i.e., liver event occurrence), given its potential liver benefit

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History of heart attack, stroke, or serious arrhythmias contraindicates the combination Uncontrolled hypertension must be addressed before considering combined treatment Personal or family history of MTC or MEN2 syndrome rules out Wegovy use entirely Substance abuse history requires careful consideration of Adderall appropriateness Severe anxiety disorders may be worsened by this combination Practical Guidance for Managing Both Medications For those who, in consultation with their healthcare providers, determine that taking both Wegovy and Adderall is appropriate, several practical strategies can help minimise risks and optimise outcomes

Expect the first two weeks to be an observation period

These findings collectively indicate that MASLD is associated with specific alterations in intestinal fungi

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