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Depression also causes cognitive decline

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doi: 10.1002/14651858.CD006787.pub2

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This breakdown of the BBB coincided with extensive microglial activation, dopaminergic neuronal degeneration, and upregulation of P-glycoprotein and 3-integrinchanges suggestive of a compensatory and potentially angiogenic response

Recognizing the role of chronic inflammation in these conditions is a crucial step toward better disease management and a higher quality of life