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Malin SK, et al

Over time, strength returns, mobility improves, and people report an improved sense of vitality and control over their body again

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Rodent studies revealed that administration of GLP-1R agonists to the central or peripheral nervous system can activate a subset of GLP1Rexpressing neurons and produce weight loss [10, 11]

It supports mitochondrial energy , glucose metabolism, nerve health, and helps recycle other antioxidants like vitamin C and glutathione

A 2021 cohort study published in Metabolism: Clinical and Experimental found that morning fasted IGF-1 administration produced 35% higher skeletal muscle Akt phosphorylation (a direct measure of PI3K pathway activation) compared to evening administration