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Another priority is the establishment of preclinical models that better simulate the heterogeneity of PD, so PLGA-based nanoparticles could be tested under physiologically relevant conditions 150

2013;85(2):74552 Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D

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Furthermore, the BHBA-induced decrease of H2AK119ub was dependent on L-type VSCCs, while the increase of H3K4me3 mainly resulted from BHBA-activated cAMP/PKA signaling (Figure 6)