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Interestingly, a 2021 study demonstrated that IGFBP2 is required for the full effect of RYGB on weight loss and early improvements in insulin action in mice 102

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A meta-analysis that combined data from systematic reviews and meta-analyses came to the conclusion that there was likely no increase in the risk of diabetic retinopathy from any of the diabetes drugs.[ref] However, this is still a side effect to be aware of and talk with your doctor about your individual risk

Regulatory note: Health Canada is warning consumers about the serious health risks of unapproved peptides