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Side Effects and Tolerability: The side effect profiles of these compounds differSSRIs are often associated with gastrointestinal and sexual side effects, whereas GLP-1 receptor agonists like semaglutide may lead to gastrointestinal disturbances but are less associated with long-term mood alterations

This factor is significant for weight loss sustaining, given that after subcutaneous semaglutide (2.4 mg) treatment suspension, studies have shown that there may be a weight regain worsening cardiometabolic parameters (60)

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GLP-1 medications influence appetite and glucose regulation, but they do not independently preserve muscle mass

The people I see in clinic, they care about getting out of a chair, playing with their grandchildren, not being admitted into a nursing home, Batsis says