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Cold sensitivity is not listed as a primary side effect in major tirzepatide trials, but patient reports suggest it occurs in a minority of users, usually early in treatment

Incorporate Strength Training and Resistance Exercise Resistance training preserves muscle mass during weight loss by signaling the body to hold onto muscle even in a caloric deficit

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[DOI] [PubMed] [Google Scholar] 108.Dobric I., Drvis P., Petrovic I., Shejbal D., Brcic L., Blagaic A.B., Batelja L., Sever M., Kokic N., Tonkic A., et al

Glucagon Aids in fat metabolism and energy expenditure